(CNN)A series of storms moving across the country will bring significant snow and ice to the north and heavy rains to the south Friday and into the weekend.
Roughly 100 million people are under some form of a winter storm watch, warning or advisory across the United States.
The storm is already affecting travel with nearly 450 flights canceled as of Friday morning, according to FlightAware.com. Airlines are issuing waivers for travelers traveling in the Midwest and Northeast.
Major metro areas on the East Coast likely will face light snow Friday ahead of and during the morning commute. The storm should move so quickly that accumulations are expected to remain low in New York and Boston.